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JASPAR JASPAR is an open access and widely used database of manually curated, non-redundant transcription factor (TF) binding profiles stored as position frequency matrices (PFM) and transcription factor flexible models (TFFM) for TFs from species in six taxonomic groups. From the supplied PFMs, users may generate position-specific weight matrices (PWM). The JASPAR database was introduced in 2004. There were seven major updates and new releases in 2006, 2008, 2010, 2014, 2016, 2018, 2020 and 2022, which is the latest release of JASPAR. Availability The JASPAR database is an open-source and freely available for scientific community at http://jaspar.genereg.net/. Similar databases TRANSFAC – Transcription Factor Database HOCOMOCO - HOmo sapiens COmprehensive MOdel COllection PAZAR - Database with focus on experimentally validated transcription factor binding sites TFe – the transcription factor encyclopedia AnimalTFDB – Animal transcription factor database PlantCARE – cis-regulatory elements and transcription factors in plants (2002) RegTransBase - transcription factor binding sites in a diverse set of bacteria. RegulonDB – Primary database on transcriptional regulation in Escherichia coli TRRD – Transcription Regulatory Regions Database, mainly about regulatory regions and TF-binding sites PlantRegMap Plant Transcriptional Regulatory Map MethMotif An integrative database of cell-specific transcription factor binding site motifs coupled with DNA methylation profiles. References |